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Sujets - Michèle

Pages: [1]
5
Douleurs & spasticité / Douleur osseuse
« le: 09 juin 2011 à 11:09:54 »
Bonjour le Monde,
à force d'éliminer, corriger et comprendre mes douleurs avec l'aide efficace de ma kiné ostéopathe, je constate qu'un douleur réccurente semble uniquement une douleur osseuse, au niveau de l'ischion droit protégé par "rien" :). Avez-vous ce type de douleur précise et comment les gérer vous ?
Merci pour votre contribution <3
Amitiés,
Michèle

6

je serai éventuellement intéressée par ce genre de lieu de vie :

http://www.autonomie-habitat.com/l_actualite.htm

Bien cordialement,
Michèle

9
Les équipements, les aides techniques / jambes bioniques
« le: 15 juillet 2010 à 20:27:42 »
http://video.rtlinfo.be/video/188205.aspx
et au journal de France 2 ce soir

10
Fonctions sexuelles, Vie affective et Maternité / fibrome uterin
« le: 05 avril 2010 à 11:23:41 »
Bonjour,
je ne sais pas si je suis dans la bonne section pour exprimer mon problème...
Jeudi, je suis allée en consultation gynéco ,après plusieurs semaines de règles hémorragiques , où il  m'a été diagnostiqué un fibrome uterin d'environ 7 cms.
Après 14 ans sans suivi gynéco, le dernier ayant était fait au CRF de Coubert où après 9 mois d'absence de règles, je me suis juste entendue dire que j'étais triste et n'avait plus aucune sensibilité... Bref, du classique.
A l'annonce ,jeudi, de ce verdict, j'ai compris et oublié de mentionner que les TR étaient de + en + difficile car non seulement ce fibrome comprime la vessie ( y'a t'il risque pour l'appareil urinaire ?) avec clonies et sueurs mais également l'ampoule rectale qui ne se remplit pas  par obstruction. Je ressorts de mon passage aux toilettes, épuisée, avec une barre douloureuse au niveau des "reins" et bien entendu une évacuation incomplète.
Parmi vous, y a t'il des femmes qui ont été concernées par ce type de problème et quelle(s) solutions ont été apportées ?
La gynéco m'a perscrit du Lutényl et un gel à la progestérone mais je doute que cela résolve le problème du fibrome. N'y a t'il pas "urgence" à intervenir chirurgicalement ?
Merci d'avance
Amitiés,
Michèle

11
Les équipements, les aides techniques / FAUTEUIL DOUCHE
« le: 21 octobre 2009 à 20:11:48 »
Bonsoir,

je vends ce modèle :

http://www.dynamut.com/fauteuil-douche-roulant-clean-p-569.html?osCsid=8ugs9vruurcislu4brvkju7hh3

utilisé 2 semaines l'an passé.

Alarmitiés,

Michèle




12
Recherches fondamentales / HEALING THERAPIES NEWSLETTER
« le: 22 mai 2009 à 09:32:00 »


HEALING THERAPIES NEWSLETTER

....................................


This is the 42nd email newsletter© associated with www.healingtherapies.info, the purpose of which is to expand the healing spectrum of people with physical disabilities.


From a holistic mind-body-spirit view, the most powerful healing comes from adopting a health-enhancing consciousness, whose overarching influence transforms the physical. This two-part article specifically discusses how life-force-rejuvenating stem cells may be key mediators of this transformation catalyzed by consciousness - from both a scientific and spiritual perspective and from a heart-moving story of forgiveness.


Please support those who have made this newsletter possible. Specifically, consider subscribing to PN/Paraplegia News (subscribe 602-224-0500 or www.pn-magazine.com) or donating to the Paralyzed Veterans of America's Research and Education Program (www.pva.org ).

....................................

ALTERNATIVE-MEDICINE BOOK


Check out Alternative Medicine and Spinal Cord Injury: Beyond the Banks of the Mainstream at http://www.demosmedpub.com/prod.aspx?prod_id=9781932603507 or Amazon.com. (rated 5 stars, highly informative). This is an instructive book for anyone, with or without disability.

....................................

Learn more about divergent function-restoring therapies for spinal cord injury at www.sci-therapies.info.

....................................

STEM-CELL CONSCIOUSNESS: THE DIVINE GROUND OF HEALING

Laurance Johnston, Ph.D. & Amanda Boxtel


In the 21st century, stem cells are going to play an ever-increasing role in restoring function lost by disability, disease, or the entropy of aging. From conception until death, they are the cells of renewal and regeneration through which many growth and healing energies are mediated.

The expression of stem cells can be positively or even negatively influenced by numerous therapies. For example, acupuncture can stimulate their expression, while chemotherapy is more toxic to them than to the targeted cancer cells. From a holistic mind-body-spirit view, the most powerful healing comes from adopting a health-enhancing consciousness, whose overarching influence transforms the physical. This two-part article specifically discusses how life-force-rejuvenating stem cells may be key mediators of this transformation catalyzed by consciousness - both from a theoretical and personal perspective.

Many stem-cell transplantation programs are emerging throughout the world targeting a variety of disorders. For example, I've reviewed over 25 such programs for spinal cord injury alone. Because they often use vastly different procedures, success varies considerably. For these nascent programs, "God will be in the details" - probably not just figuratively.

One oft-ignored detail is that consciousness of individuals involved in the process of transplantation of stem cells may influence outcome. As living omnipotent holographic manifestations or determinants of our greater selves, the life force power of these cells will be affected by the consciousness of the stem-cell recipient, donor, and those who prepare, handle, and otherwise nurture the cells. As such, to maximize potential benefits, stem-cell patients should factor in the role of consciousness through the attitudes and emotions they adopt surrounding treatment.


Life and Teachings of the Masters of the Far East

Ancient wisdom often has much validity even for the most contemporary scientific issues. For example, long before stem cells became a blip on modern science's radar, the influence of consciousness on their expression was discussed in the Life and Teachings of the Masters of the Far East (Baird Spalding):


1) "As the cell divides and creates a new cell, our thought is implanted upon it.In the first cell, all is perfect. That cell was first known as the Christ cell." (i.e., the anointed cell)  "It is always just as young as ever it was. It never takes on old age. It is the primal spark of life. When we implant in it our thoughts of limitation or old age, or any condition outside of perfection, the body responds. Cells born from the first cell take on its image. Originally it is the image and likeness of God. It is perfect in every way. But it becomes the form we carry in our minds.if we carry the image of perfection always, what will it do for these cells? It will build perfection." (Vol. 6, Page 78)


2) "The moment a cell divides itself from the parent cell, and the instant before it divides itself, it takes on the exact image of the parent. As it goes out, it comes under the influence of this imperfection that we think for ourselves. What happens? We see the vibrations of the cell lowered, and in some instances when it attaches itself to the organ where it belongs, it is a dead thing.The very thought influence of imperfection influences that cell until it dies. The vibrations go so low that the dynamic influence flows out." (Vol. 6, Page 92)


Scientific Mechanisms

Scientists have proposed many physiological mechanisms by which emotions, attitudes, and overall consciousness can potentially transform our health and influence stem cells. For example, Dr. Bruce Lipton hypothesizes that our consciousness affects DNA expression through influencing proteins embedded in our cell membranes (The Biology of Belief, 2005). 


As shown in Menninger Clinic experiments, individuals are able to shift consciousness in a way that can alter the body's electromagnetic dynamics. Lipton hypothesizes that this alteration changes the physical configuration of membrane proteins, in turn, affecting communication between the outside and inside of cells. Roughly speaking, this consciousness-driven energy is like a radio signal triggering the garage door to open. This opening initiates a cascade of physiological events which regulate gene expression and, in turn, cell fate, potentially in a life-enhancing direction.


Scientists, indeed, have shown that the subtlest of energies affect stem-cell expression or viability. For example, these cells are exceptionally sensitive to cosmic radiation (Encinas, JM, et al. Experimental Neurology, 210, 2008). In another example, the acupuncture system and stem cells are closely linked through a network composed of under-differentiated, electromagnetically sensitive cells created early in embryogenesis before the formation of other body systems (Shang C. Life Sci, 68(12), 2001).


If such subtle influences can affect stem-cell expression, undoubtedly embracing a health-enhancing consciousness that opens up the spigot for divine, life-force energy in its many rose-by-any-other-name manifestations can do so also (e.g., qi in China, prana or akasha in India, nilch'i or Holy Wind by the Navajo or Diné, Yesod in the Jewish Kabalistic tradition, or the Christian Holy Spirit).


Forgiveness: "Arise-and-Walk" Consciousness


Forgiveness is a state of consciousness conducive for healing in many spiritual traditions. For example, a 2006 article entitled "Healing in Islam," discusses how forgiveness, a superior moral trait in the Qur'an, promotes a healing consciousness (http://www.metanexus.net/conferences/pdf/conference2006/Imam.pdf).


Perhaps the most well-known example - especially relevant to co-author Amanda Boxtel's experience - is Jesus' healing of paralysis through forgiveness (Matthew: 9:2-7):


".and he said to the paralytic, Have courage my son; your sins have been forgiven.. For which is easier to say, your sins have been forgiven, or to say, arise and walk?  But that you might know that the Son of man has authority on earth to forgive sins, then he said to the paralytic, Arise, take up your quilt and go to your home. And he rose up and went to his home."


Healing forgiveness can be contextually understood within the ageless wisdom of the "Perennial Philosophy."   In introducing The Song of God: Bhagavad-Gita, Aldous Huxley described this philosophy in which our individual consciousness is part of a Divine Ground referred to differently in world religions (e.g., Godhead, Pure Light of the Void, Unity of Allah, etc):


"First: the phenomenal world of matter and of individualized consciousness - the world of things and animals and men" [including their injured spinal cords and stem cells] "and even gods - is the manifestation of a Divine Ground within which all partial realities have their being, and part from which they would be non-existent."


Basically under this philosophy, condemnation creates a perceptual prison in which you are separated from your fellow man, greater unity, and larger self. Through your duality-based judgments of good and bad, this prison isolates you from the healing energies available as part of your inherent connection to the "Divine-Ground."


Through true non-judgmental letting go and not just righteously forgiving the "jerk" who caused your problems, you are forgiving your greater self. From the Perennial Philosophy viewpoint of unity, when any "Son of man" forgives another, he forgives himself of his greatest sin: a belief that we exist in separation from the Divine and all of its expressions.


Although real forgiveness is challenging, you do it in self interest under the golden-rule reciprocity principle emphasized by most religions. Through true forgiveness, the perceptual prison tumbles like the walls of Jericho, you reestablish at-one-ment with the Divine Ground, and healing energies previously held in abeyance flow in. In a twinkling of an eye your consciousness is healed, which - as above, so below - percolates into the physical.


Forgiveness & Stem Cells

In 2007, Amanda Boxtel traveled to India for treatment with human embryonic stem cells. In India, the use of such cells is allowed if the condition or disorder is considered incurable, as is the case with spinal cord injury. The stem cells implanted in Amanda were derived from a surplus fertilized egg from an IVF program. In other words, they were developed with the intention to create life and, hence, were endowed with the life-force consciousness of that purpose.


As someone whose paralysis had been unchanged since injury over 15 years earlier, Amanda regained impressive function. Medical professionals consider such improvement extraordinary for a long-term injury like she possessed.


PART 2


June 25th, 2007 marked a new beginning and my journey of awakening my body after fifteen and a half years of paralysis.  On this day exactly nine months ago (in a time-frame akin to pregnancy from conception to birth) I received my first human embryonic stem-cell injection in Delhi, India.  In essence, I infused my body with the divine beginnings of life.  Today I continue to visualize my little baby embryonic stem cells bringing new life to my body; gestating into fully developed neuronal cells, and rewiring my spinal cord creating intricate dendrite pathways that will one day enable me to walk again. 


I have matured in the course of these past nine months and I have a greater understanding of what it takes for the human body to truly heal.  My journey of awakening and healing my body is more than just the physical.  I marvel at the possibility of how I can actualize divine consciousness within my own physicality.  I believe that my physical body itself has its own consciousness, with each organ, tissue, and miniscule cell displaying their own consciousness respectively. 


If I try to dissect my healing, my practice encompasses every aspect of my inner and outer self.  I understand that my mental consciousness, which is manifested in my thoughts, beliefs, attitudes and ideas, affects both the cells in my physical body and influences the expression of the human embryonic stem cells that have been injected into me.  I consciously think in my mind: perfection manifests perfection.  Through meditation, visualization and energetic healing I have explored tapping into my soul and intuitive or karmic self-depicted as seeds of perception and inner knowingness-to manifest healing on a deeper cellular level.  My healing practice also addresses my spiritual, and energetic self that I describe as a holographic matrix of vibrational energy that bleeds in and out of my physical self; and my emotional self, which stems from my feelings and opening my heart like a lotus blossom with a thousand petals that is filled with love, truth, and forgiveness. 


While I believe that my consciousness and every consequent action in my waking life have the potential to affect and sculpt my reality now and every moment forward, I never understood the power of forgiveness to heal my physical body until I experienced this phenomenon first hand.  I discovered that by exposing my deep emotional self to the vulnerability of true forgiveness and acceptance, such paranormal healing is possible for the layperson like me.not just the yogis of the Himalayas. 


I discovered that I was a prisoner in my own body.  I had to set myself free mentally, emotionally, and spiritually for true healing to take effect in my physicality.   Forgiveness set me free.  Forgiveness meant choosing to love the individuals in my life who had caused me such pain over years past.  Mostly, this act of forgiveness meant renouncing my pent up anger toward my father by resolving to love him with compassion combined with a genuine willingness to forgive.   


Writings through the ages and various alternative healing therapies such as Yoga and Pranic Healing bring light to the fact that unresolved emotions can manifest as dis-ease on the cellular level in the physical body.  Could my paralysis rooted in the lower half of my physical body be a result of years of suppressed emotions and my inability to speak up for myself at a young age?  I had an epiphany that possibly the severe trauma of my spinal cord injury complete at the eleventh and twelfth vertebrae blocked the life force energy flow to and from my root chakra, and consequently affected the back-support of my life.  Interestingly, I learned that the root chakra is located in the bones, feet, knees, legs, perineum, and coccyx.  It is also associated with revealed anxieties and feelings of victimization from shame or a lost connection with family and roots.  Could the suppression of my father's abuse as a young child have played a critical role in my paralyzed adult body?  These are all mind boggling thoughts.


My life pattern has been suppression.  During a powerful meditation on the seventh week of receiving human embryonic stem cell treatment in Delhi, India, I surrendered to this life pattern.  The date was Sunday, August 12, 2007.  I sat in an oversized chair with my eyes closed.  I began voicing out aloud abundance and prosperity in my life, thinking good things, accepting myself as I am and feeling truth resonate as a song in my heart.  I praised myself with self-love understanding that my body is a miraculous divine temple.  I was at peace and I affirmed that I was willing to release the pattern that created my paralysis.  I whispered to myself,


"I am whole, I am healthy, and I am very secure in this eternal life.  I have no fears.  I know that life always supports me.  I let go and I accept myself." 


At this point I began a quiet meditation and visualization.  In my mind I affirmed:


"I accept myself.  I love ME.  I have abundance.  I have prosperity.  I am beautiful.  I have a clear face.  I have strong powerful legs.  I can pee all on my own.  I can empty my bowels.  I am happy.  I am loved by Dale and I am in love.  I have everything I want right here, right now.  I am an author.  When I write, I touch hearts and souls."


I visualized the adult Amanda extending my arms out to a little child Amanda.  That child became a speck that I placed into a corner of my heart.  I avowed, "I will always be there for you, Little Amanda, no matter what."  I then imagined the same for anyone else I wanted to forgive, shrinking them to a speck and placing them in my heart and stating, "I love you, I forgive you." 


Lastly was my father.  I pictured him through the eyes of my eleven-year-old self before Dad committed suicide.  As I shrunk Dad into a speck and placed him into my heart tears streamed down my face.  I voiced out aloud,


"I forgive you Dad.  I release you.  I set you free.  Go.  Be free Dad.  You are now free of pain and turmoil.  You are a free spirit to soar.  I forgive you.  I love you.  I bring you into my heart with love and forgiveness." 


I sat in silence and I cried gut-wrenching sobs.  As my heart opened I felt a huge release.  I felt whole.  I was changed. 


Since receiving HESC treatment, my legs showed signs of renewed muscle power for the first time in fifteen and a half years.  I had flickers of quadriceps, gluteals, and hip flexors in both legs, a hamstring in the left leg, and toes that wiggled ever so slightly on the left foot.  I was beginning to void my bladder on my own, which was a miracle in itself.  My right leg was less responsive however.  I desperately wanted the hamstring to fire in my right leg and for my right toes to wiggle.  I tried relentlessly, willing with all my might.yet nothing.


The very next day after my powerful mediation of forgiveness, I witnessed true healing take place in my body-my right leg came alive!  On Monday, August 13, 2007 I underwent the final spinal procedure of my two-month HESC treatment.  I recorded the series of events that took place that day in my journal:


After receiving my final big dose of stem cells, Dr. Ashish made a pact with me, which was settled with a firm handshake.  He said, "Lie flat on your back until 7:30 p.m.  Do not move your body at all.  At eight o'clock I want you to move your right hamstring with the same intention that you used for your left.  Deal?"

"Yes Dr. Ashish.  Deal!  I'll move my right hamstring, I promise!"  I made this statement with complete confidence.and in front of Dale, with both of our eyes focused on my lower right leg as I lay on my side isolating my upper body and hip flexors; I moved my right hamstring on command!  My leg and foot moved backwards from the knee down.  The movement was slight (an inch or two is all) but it was there.  I then sat up with glee and said, "Let me try my toes."

With the same intention, I moved my right toe repeatedly.  Dr. Ashish came in to check after 8 p.m. and upon hearing my news he high-fived my right hand in the air with elation. 

"See, I told you.  Anything is possible Amanda.  You will continue to see improvements."

As I lay flat that evening on a thin hospital bed, Dale curled up next to me.  He was exhausted and jet-lagged.  His feet lay next to mine.  All of a sudden I felt a deep sensation in my right foot as though he had rubbed it with his foot.  I sat up and looked at our feet.  They were still.

"Did you rub my foot with your foot?"  I asked inquisitively. 

"Yes, did you feel that?"

"Yes, do it again!"  And Dale rubbed the bottom of my foot over and over.  I could feel a deep sensation and I knew he was there, rubbing away.  My leg didn't spasm at all.  I could simply feel his rubbing deeply underneath my skin.

"Can you feel it now?"  He asked.

"No.."  I hesitated as I looked at him with disappointed eyes. 

"Hah!  I was testing you.I stopped.  What about now?"

"Yes..yes..and yes!"

Dale had witnessed three little miracles in the span of an hour.  He was speechless.  He couldn't believe what he was seeing with his own eyes.my body was coming alive.


The forgiveness that flowed through me created the divine ground which nourished the transplanted embryonic stem cells so they could thrive and bear the fruit of restored function.  I realize that forgiveness has the potential to affect my consciousness and heal my body on levels that were once unimaginable.  Forgiveness allowed my spirit and soul to soar, and freed me from the prisoner that was me, shackled in my own body.


© 2009 www.healingtherapies.info ALL Rights Reserved


13
Scandale de grande ampleur dans l'industrie pharmaceutique
16 mars 2009 11:35, Les mots ont un sens, par Napakatbra 

Scandale industrie pharmaceutique. Scandale industrie pharmaceutique. Scandale de grande ampleur dans l'industrie pharmaceutique - LMOUS
Des millions de patients sont concernés dans le monde. Dr Scott S. Reuben, un des chercheurs américains les plus prolifiques dans le domaine du traitement de la douleur postopératoire, a fabriqué de toutes pièces la plupart des données de ses recherches, depuis 1996, au profit de plusieurs géants pharmaceutiques. Pfizer et Merck notamment.

Un Madoff de la médecine (imaginaire)

Dr Scott S. Reuben, chercheur anesthésiste à Springfield (Massachusetts) et praticien au Centre médical de Baystate, n'a jamais effectué les essais cliniques qu'il a décrit dans au moins 21 de ses 72 articles scientifiques publiés depuis 1996 ! C'est le porte-parole de l'hôpital qui a lâché la bombe, relayé par le New-York Times du 10 mars. La fiabilité de l'ensemble de son oeuvre est aujourd'hui remise en cause.

Or, en une douzaine d'année, Scott Reuben avait révolutionné le traitement des douleurs postopératoires. Ses études avaient notamment permis aux médicaments comme le Celebrex, le Lyrica et le Dynastat de Pfizer, l'Effexor de Wyeth, ou le Vioxx de Merck d'être utilisés et autorisés par la Food and Drug Administration (FDA). Les traitements promus par le chercheur concernent aujourd'hui des millions de patients dans le monde. Et beaucoup de milliards de dollars.

Hasards ou coïncidences

Outre le fait que Pfizer a attribué, ces dernières années, de nombreuses études à Reuben, le chercheur était aussi payé par la firme pour animer des conférences totalement dévolues à la gloire de ses médicaments, selon le Wall Street Journal. Le géant pharmaceutique se défend en invoquant d'autres études "indépendantes" sur les médicaments concernés. "Nous attendons des chercheurs indépendants qu'ils soient sincères et motivés par le désir de faire avancer les soins aux patients. Nous sommes très déçus d'apprendre ces allégations au sujet du Dr Scott Reuben" a notamment déclaré le porte-parole de Pfizer. La larme à l'oeil...

"Lorsque les chercheurs sont redevables d'entreprises pour une grande partie de leurs revenus, il existe une tendance évidente à obtenir des résultats qui leur sont favorables", s'est plaint le Dr Jerome Kassirer, ancien rédacteur en chef du New England Journal of Medicine et spécialiste des conflits d'intérêts dans l'industrie pharmaceutique. Etonnant.

Un plan qui se déroule (presque) sans accroc

D'une part, les compagnies pharmaceutiques fournissent elles-mêmes les données nécessaires à l'évaluation des médicaments, en vue d'obtenir les autorisations de mise sur le marché. D'autre part, elles embauchent les médecins pour réaliser les essais complémentaires sur les médicaments approuvés. Et enfin, elles mènent des actions de démarchage auprès des médecins de ville pour leur fourguer leur camelotte. La boucle est bouclée, sans accroc, et des milliers de patients se retrouvent... accros.

Seule ombre au tableau : chaque année, des dizaines de médicaments sont retirés du marché pour leur dangerosité, alors qu'ils ont passé toutes les étapes des évaluations sanitaires. Le Vioxx, par exemple, sur lequel a travaillé Reuben. La FDA estime que ce traitement largement utilisé contre l'arthrite, a provoqué depuis 1999 aux États-Unis 160 000 crises cardiaques et attaques cérébrales et serait à l'origine de 27 785 décès. Il a été soustrait des pharmacies en 2004 par son fabriquant (Merck), alors que les rumeurs de dangerosité commençaient à se faire insistantes.

Les scandales se suivent et se ressemblent

Le prochain scandale pourrait d'ailleurs bien éclater dans les toutes prochaines semaines à propos du Seroquel d'AstraZeneca. Selon de nombreuses sources, la firme tenterait de garder secrets des documents montrant qu'elle connaissait les effets secondaires graves de son médicament, sans jamais les avoir révélés. Mais 4,5 milliards de dollars d'aumônes annuelles ne valent-ils pas quelques messes basses ?

(Article publié sur le site "Les mots ont un sens")

 


14
Les escarres / soin anti escarres
« le: 24 février 2009 à 20:40:49 »
http://aromathera.over-blog.com/article-25534374.html
j'ai trouvé ce lien hier. Quelqu'un(e) connaît ?
Pour ma part, je suis en train de tester l'huile essentielle de lavande fine conseillée par mon infirmier, très efficace en ce qui me concerne.
Amicalement
Michèle

15
Exprimez-vous ! / http://www.viedemerde.fr/
« le: 13 février 2009 à 15:02:54 »

16
Exprimez-vous ! / 12 000€
« le: 22 janvier 2009 à 18:11:17 »
Concrètement, que pourrait faire ALARME avec les 600 x 20 € environ des adhésions des membres fréquentant le forum sans avoir adhérer à l'asso ?
Y a t'il des demandes spécifiques de chercheurs auquelles ALARME ne peut favorablement répondre faute de moyens alors qu'elles seraient d'une importance significative pour la communauté des Blessés médullaires ?
Michèle

17
Exprimez-vous ! / ADHERER A L'ASSO
« le: 25 novembre 2008 à 10:02:04 »
Bonjour,
Pourrions-nous savoir quelle raison empêche les accoutumés, habitués et autres ... profitant du forum et de la richesse de ses infos d'adhérer à l'association ?
Amicalement,
Michèle

19
Activités contre Escherichia coli


Les propriétés antibactériennes de cinq huiles essentielles ont été évaluées et quantifiées sur une souche non toxigénique d’Escherichia coli. Cinq huiles essentielles connues pour leurs propriétés antibactériennes ont été examinées et les plus actives ont été sélectionnées pour d’autres essais. L’origan et le thym avaient les propriétés bactériostatiques et bactéricides les plus fortes, suivis par le laurier et le clou de girofle.
In vitro, l’origan et le thym possèdent des propriétés colicides et colistatiques significatives qui se manifestent dans le cadre d’une large rangée de température et qui sont améliorées par l’addition d’agar-agar comme stabilisateur. Les huiles essentielles de clou de girofle et de laurier sont moins actives6.

http://www.nutranews.org/article.php3?id_rubrique=24&id_article=58

20
Dr. Lima (Lisbonne - Portugal) / OLFACTORY TISSUE TRANSPLANTATION
« le: 18 septembre 2008 à 14:49:27 »


HEALING THERAPIES NEWSLETTER

....................................


This is the 38th email newsletter© associated with www.healingtherapies.info, the purpose of which is to expand the healing spectrum of people with physical disabilities, especially spinal cord injury (SCI) and dysfunction.


This issue provides an update on Dr. Carlos Lima's function-restoring procedures for implanting regenerative-endowed olfactory tissue into the patient's spinal-cord injury site. The update revolves around the 3rd International Symposium for Olfactory Mucosa Autografts and Rehabilitation held in May in Kefalonia, Greece.  In the article, 1) Lima shares his insights on important issues surrounding his program, and 2) Dr. Jean Peduzzi-Nelson, Wayne State University summarizes supporting studies using the procedures in rats. Her insights indicate that it is the stem cells within the olfactory tissue, and not the olfactory ensheathing cells (OECs), that are providing most of the benefit.


Please support those who have made this newsletter possible, including PN/Paraplegia News (subscribe 602-224-0500 or www.pn-magazine.com , and the Paralyzed Veterans of America (www.pva.org ).

....................................

ALTERNATIVE-MEDICINE BOOK


Check out Alternative Medicine and Spinal Cord Injury: Beyond the Banks of the Mainstream published by Demos Medical Publishing either at http://www.demosmedpub.com/prod.aspx?prod_id=9781932603507 or Amazon.com. (rated 5 stars, highly informative). This is an informative book for anyone, with or without disability.

....................................

Learn more about divergent function-restoring therapies for spinal cord injury at www.sci-therapies.info (or www.sci.is ).

....................................


STUDY PARTICIPANTS SOUGHT WITH SENSORY OR MOBILITY IMPAIRMENTS


Interested in making some extra money?


If you have a sensory impairment or mobility impairment, you may be eligible to participate in a new NIH-funded research project at Washington University (St. Louis).  This research aims to understand what people with sensory and/or mobility impairments do in their daily life, how their environment affects their community participation and what, if any, help they need to complete these activities. This web-based assessment contains a set of two surveys and will take approximately one hour to complete. If you are interested, click on the following link (http://emc.wustl.edu/ncmrrstudyad.htm).

.......................................


OLFACTORY-TISSUE TRANSPLANTATION FOR SCI - FIVE YEARS LATER

(Adapted from August 2008 PN/Paraplegia News article)


INTRODUCTION

Laurance Johnston, Ph.D.


Under the traditional Hippocratic Oath, physicians swore to Asklepios, the Greek god of medicine who healed people and made them immortal. Asklepios' healing was unacceptable to Hades, the god of the underworld, who considered these souls his property. Hades persuaded his brother Zeus, the king of gods, to hurl a lightning bolt through Asklepios' head. Zeus declared that medicine thereafter could only be palliative, i.e., make patients more at ease while they either died or got well on their own. Cures were forbidden.

Given the immortality of stem cells and their ability to cure and restore function lost by disability, disease, or the entropy of aging, we may again incur Zeus' wrath as we develop their full healing potential. Although risking being zapped to the Elysian Fields where Zeus' victims were destined, numerous innovators throughout the world are developing stem-cell approaches to restore some function after spinal cord injury. 

One of the more promising approaches was first introduced in a May 2003 PN article (posted www.healingtherapies.info). That article specifically described Portuguese neuropathologist Dr. Carlos Lima's procedures for implanting regenerative-endowed, stem-cell-rich, olfactory tissue isolated from the patient's nose into the spinal-cord injury site.

The 5+ years of experience using these procedures was recently reviewed at the 3rd International Symposium for Olfactory Mucosa Autografts and Rehabilitation held May 9-10th in Kefalonia, Greece - the birthplace of Asklepios, Hippocrates, and Western medicine in general.


In addition to the transplantation technique itself, the meeting focused on how to best maximize restored function through post-surgical, aggressive rehabilitation. Although the transplantation procedures were developed in Portugal, many of Lima's patients have undergone post-operative rehabilitation in US facilities. The insights gained at them are invaluable for not only assessing the potential of Lima's program, but also providing direction to other function-restoring approaches that inevitably will be developed in the future.


In this article, innovator Lima shares his insights on important issues surrounding his program, and Dr. Jean Peduzzi-Nelson will summarize for the first time supporting studies using the procedures in rats. 


Procedures

Because olfactory tissue is exposed to the air we breathe, it contains cells with considerable turnover potential, including renewable neurons, stem cells, and olfactory ensheathing cells (OECs).  Briefly, stem cells are progenitor cells that have the potential to transform into CNS tissue, and OECs produce insulating myelin sheaths around regenerating axons. Lima transplants whole olfactory tissue because he believes that more than one cell type is needed to maximize regeneration.


Lima's Portuguese surgical team and international colleagues have treated nearly 130 patients from throughout the world. Many have reported functional recovery, ranging from the subtle to the fairly dramatic. Recently, the World Technology Network named Lima as a finalist for a prestigious innovation award in health and medicine.





A key procedure is the collection of about one fourth of the patient's olfactory tissue through procedures that maximize the harvesting of that tissue but avoids the collection of closely associated nasal respiratory tissue. Because the transplanted tissue is from the patient, immunological rejection is minimized. The injury site is then surgically exposed, and regeneration-blocking scar tissue is removed. The isolated olfactory tissue is dissected into small pieces while immersed in the patient's cerebrospinal fluid. The pieces are then implanted into the cavity.


INSIGHTS ON USING OLFACTORY MUCOSA AUTOGRAFTS (OMA)

Carlos Lima, MD, Egas Moniz Hospital, Lisbon, Portugal


I'm focusing my discussion on three key issues relevant to our OMA program: 1) the post-injury disconnection syndrome; 2) the regeneration-blocking scar; and 3) the use of whole olfactory tissue.


Disconnection Syndrome

Because SCI represents a disconnection syndrome, I believe functional recovery will require extensive reorganization of the neural circuits surrounding the injury site. This can be achieved through connection-building cell-transplantation strategies (e.g., OMA) followed by functional rewiring through post-operative, rehabilitation programs.


Studies suggest that there is little regeneration of the long, movement-controlling motor-neuron tracts that run down the spinal cord from the brain in the mature nervous system. As expected, the injury alters the sensory input that the brain receives from paralysis-affected body areas, which, in turn, causes brain neural circuits to reorganize. Although this reorganization promotes the death of injury-affected motor neurons emanating from the brain, it stimulates the sprouting of spinal-cord connective neurons (called propriospinal neurons) and the creation of new, function-restoring circuits between them in incomplete injuries.  This means that the modified and newly created neural pathways will be the ones responsible for mediating recovered function in patients with incomplete injuries rather than the pathways that dominated before injury. 


To maximize restored function after OMA-transplantation, we believe intense rehabilitation is required - our ultimate goal being the patient relearning to walk.  Over-ground gait training with true weight bearing by the hips, knees and feet is especially important and should stimulate or strengthen the newly created neural pathways. Freedom of movement unrestricted by braces will facilitate the development of new motor patterns and functional connections, while hip and knee immobilization may limit such development. Likewise, we should not restrict rehabilitation to "normal" training patterns because "abnormal" conditioning will probably be needed to re-establish motor skills that now depend upon different nervous-system rewiring.


Scar

After injury, neural support cells (e.g., astrocytes) and cells from neighboring connective tissue (i.e., fibroblasts) generate a dense glial/connective scar at the injury site, which is a barrier to regenerating neurons.  Overall, from the experience we have accrued using OMA procedures for chronic injury, we have concluded that the scar is a "no-man's land" with respect to regeneration. Therefore, we believe it is important to remove it before implanting enough regenerative-rich olfactory tissue to bridge both the normal rostral and distal (i.e., top & bottom) stumps of the spinal-cord. As our neurosurgical skills improve with experience, combined with the capability to monitor through electrophysiological and imaging methodology, the overall safety of scar removal will greatly increase.


Cell Source

In many severe injuries, the neuroplasticity or adaptability of residual connections will be inherently limited without some kind of bridging and rebuilding of nerve circuits. As such, it makes sense to transplant the patient's own olfactory tissue - endowed with regenerative stem/precursor cells - into the patient's injury site. We expect the implanted olfactory tissue to mimic its natural properties of replacing and repairing and will depend on Nature's wisdom to do so when grafted into the spinal cord. Using these implantation procedures combined with rehabilitation, we believe we can bridge and re-establish function-restoring neural connections after SCI.


Cumulatively, it is a long and challenging process, perhaps taking years of effort to walk unassisted. But, nevertheless, it is an attainable goal with hard work and a steadfast conviction of what is, indeed, possible after injury. As Lao-Tsu stated: "A journey of a thousand miles begins with a single step."


INSIGHTS FROM ANIMAL STUDIES

Jean Peduzzi-Nelson, Ph.D., Wayne State University, Detroit, Michigan


My laboratory evaluated Dr. Carlos Lima's OMA approach using a rat model of contusive spinal cord injury. 


My early studies generated mysterious results.  Although transplants of either olfactory mucosa or bone-marrow-derived stem cells improved locomotion in rats with chronic, severe SCI, the combination of these two treatments resulted in much less improvement than either treatment alone.  This didn't make sense because we thought that such a combination would produce much better recovery.  However, more recent studies (supported by France's ALARME foundation) solved the mystery and provided further insight into the OMA mechanism. 


OMA transplants produce significant functional improvement  as measured by "blinded" assessors who did not know what treatment the rat received.


Interestingly, the olfactory-derived stem/progenitor cells produced slightly more functional improvement.  For several years, experts have assumed Lima's clinical results were due to the OECs within the olfactory tissue. Indeed, this OEC emphasis has been embraced by Australian and UK researchers. However, our results strongly suggest that it is the stem-cells and not the OECs that are primarily responsible for functional improvement. Long suspected by Lima, it justifies his use of whole olfactory tissue rather than merely the OECs isolated from such tissue.


Another fascinating result was that although the stem cells produced greater functional improvement, it did not reach statistical significance.  The reason behind this and probably the reason that the previous combination treatment failed was that stem cells that are not from the same animal or an animal that is closely tissue matched (similar to blood matching) are not as effective. 


In the latest study, the various treatments were done in both inbred (closely matched - similar to a transplant from a sister or brother that have the same blood and tissue type) and outbred strains (similar to a transplant from a cousin that may not be of the same blood and tissue type).  Each inbred strain received cells or tissue from the same inbred strain, and each outbred strain received cells or tissue from the same outbred strain.


Results indicated that functional improvement was obtained when either olfactory or bone-marrow-derived stem cells are used in the inbred strain but not when used in an outbred strain.  It means that stem cells from the same individual or a closely related matched individual might cause functional improvement, while cells or tissue from a distantly related individual would not.  The reason could be that the stem cells that are foreign do not grow and mature as well, and therefore do not cause functional improvement.  There may also be some rejection of the foreign cells.  Although stem cells are generally not rejected, when the stem cells from a distantly related animal mature, they may acquire characteristics that the recipient considers foreign.


Now the mystery is solved concerning the combination treatment. Most likely, by combining two treatments in an outbred strain, it produced a greater rejection of the cells as foreign.  In conclusion, our findings support 1) the idea that olfactory-derived stem cells are responsible for the improvement after using function-restoring OMA procedures, and 2) the importance of using one's own stem cells for functional recovery. 


© 2008 www.healingtherapies.info ALL Rights Reserved

Si quelqu'un(e) veut traduire...
Amitiés
Michèle

21
Quelqu'un(e) peut il m'indiquer un hotel accessible et adapté sur la ville de préférence ou alentours (pas trop loin)
Merci
Amicalement
Michèle

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